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Contraindicated (1)pentobarbital will reduce the level or result of lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with potent CYP3A4 inducers may result in decreased serum concentrations and loss of antimalarial efficacyfentanyl transdermal and pentobarbital both of those raise sedation. Ke